A one-step multiplication curve is a graphical model of bacteriophage growth where host cell lysis and simultaneous virion release cause a steep rise in viral titer, followed by a decline as remaining viral particles degrade when host cells are depleted.

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Unlike the growth curve for a bacterial population, the growth curve for a virus population over its replication cycle does not follow a sigmoidal curve. It begins with inoculation, where the virus infects cells, followed by a flat eclipse phase, a burst phase, and a eventual decline.

Viral Growth Curve

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

OpenStax Microbiology Textbook

The eclipse phase is the interval in a viral growth curve during which viruses bind and penetrate the host cells, resulting in no detectable virions in the surrounding medium.

Eclipse Phase of Viral Growth

A viral burst is the simultaneous release of newly assembled virions from lysed host cells into the surrounding environment, resulting in a rapid increase in the viral population.

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